Adrenaline Receptor

Position - a position held Xaperones ™ adrenaline receptors, requires a lock. Xaperone ™, as the adrenaline receptor binding, researchers can determine the structure of the techniques of X-ray crystallography. The results were published in the journal Nature.

Perspectives of Medicine

The former is not only a scientific breakthrough, a recently developed technique offers hope to the prospects of medicine. button adrenaline inhibitors and beta blockers are widely used in asthma medications, such as Target. The second is used in medicine for heart disease in the world.

But the statement is not limited to the disease of asthma or heart problems. 30% of all drugs sold in pharmacies of the same receptors on or off. With a recently developed technique, the receiver and to determine the validity of new medicines or better is a necessary first step is the development, which could be described now.

switches in the body as a receiver

Adrenaline is a hormone released under stress. Messenger, and the heart beat faster as an immediate source of energy used in our sweat suddenly cause for which the sugar molecule released. These reactions are the result of the fact that a particular key (also known as beta2-adrenergic receptor) binds to adrenaline. The key steps in the membrane surrounding the cells. When the receptors of adrenaline, a single cell of the body in preparation for the rest of the fight or flight reactions to stress, as you know.

It is not possible to determine the structure of the traditional methods of these switches. Swaying motion and position of constant change, even when the signal molecule, such as the absence of adrenaline. As the ice cream at Stanford University, Jan Steyaert, and colleagues, the researchers were able to position "to" Enable adrenaline. To this end, to make this transition gives a key to the locked position and switch to another leads to halt Xaperone ™ is used. This structure has been determined using X-ray crystallography, the "frozen" in place.