CLINICIAN’S CORNER

CLINICIAN’S CORNER
Diet and Physical Activity in Severely Obese Adults
Goodpaster and colleagues assessed the effects of a 1-year intensive lifestyle intervention
on weight and cardiometabolic risk among adults with severe obesity who were
enrolled in a randomized trial that assigned participants either to 12 months of a
reduced-calorie diet plan and prescribed moderate-intensity physical activity or to the
same 12-month dietary intervention with the physical activity program delayed for
6 months. The authors report that participants in both groups experienced clinically significant
weight loss and favorable changes in cardiometabolic risk factors. In an editorial,
Ryan and Kushner discuss obesity treatment and the state of obesity research.